Patents

Hanna G, Woodfield G, Belluomo I

The invention relates to biomarkers, and to novel biological markers for diagnosing colorectal cancer. In particular, the invention relates to the use of these biomarkers as diagnostic and prognostic markers in assays for detecting colorectal cancer, and corresponding methods of detection.

Hanna G, Romano A

The disclosure provides a thermal desorption (TD) tube sampler. The sampler comprises a first connector configured to reversibly connect to a TD tube containing a sample, and a second connector configured to couple to a direct injection mass spectrometer.

Hanna G, Vadhwana B, Belluomo I, Boshier P.

The invention relates to a method for diagnosing a subject suffering from cancer, or a pre-disposition thereto. The method comprises detecting, in a bodily sample from a test subject, the concentration of a signature compound resulting from the metabolism of at least one sugar, and/or at least one amino acid or a precursor thereof, and/or at least one polyol present in a composition previously administered to the subject.

Hanna G

A method for diagnosing or prognosing a subject suffering from cancer, comprising analysing the level of at least one signature compound in a bodily sample from a test subject. Preferably the sample is taken from the breath of the subject. The method may be used in the diagnosis or prognosis of oesophagogastric cancer.

Hanna G, Romano A

The disclosure provides a thermal desorption (TD) tube sampler. The sampler comprises a first connector configured to reversibly connect to a TD tube containing a sample, and a second connector configured to couple to a direct injection mass spectrometer.

Hanna G, Boshier P

The invention relates to a method for diagnosing or for providing a prognosis of a subject suffering from oesophagogastric cancer, or a pre-disposition thereto. The method comprises analysing, in an endoluminal sample obtained from a test subject, the level of at least one biomarker compound selected from the group consisting of: acetone, acetic acid, butyric acid, pentanoic acid and hexanoic acid.

Hanna G, Markar S

The invention relates to biomarkers, and to novel biological markers for diagnosing various conditions, such as cancer. In particular, the invention relates to the use of these compounds as diagnostic and prognostic markers in assays for detecting cancer, such as pancreatic cancer and/or colorectal cancer, and corresponding methods of detection.

Hanna G, Vadhwana B, Belluomo I, Boshier P

The invention relates to a method for diagnosing a subject suffering from cancer, or a pre-disposition thereto. The method comprises detecting, in a bodily sample from a test subject, the concentration of a signature compound resulting from the metabolism of at least one sugar, and/or at least one amino acid or a precursor thereof, and/or at least one polyol present in a composition previously administered to the subject.

Hanna G, Boshier P

The invention relates to a method for diagnosing or for providing a prognosis of a subject suffering from oesophagogastric cancer, or a pre-disposition thereto. The method comprises analysing, in an endoluminal sample obtained from a test subject, the level of at least one biomarker compound selected from the group consisting of: acetone, acetic acid, butyric acid, pentanoic acid and hexanoic acid.

Hanna G, Belluomo I, Boshier P.

The invention relates to the detection of biomarkers, and methods, compositions and kits for the detection of such biological markers for diagnosing various conditions, such as cancer. In particular, the invention relates to the detection of compounds as diagnostic and prognostic markers for detecting cancer, such as oesophago-gastric cancer.